Sequence: CRRLRHLRHHYRRRWHRFRC
| Experiment Id | EXP002073 |
|---|---|
| Paper | Surface-Engineered Mucus Penetrating Nucleic Acid Delivery Systems with Cell Penetrating Peptides fo |
| Peptide | M9 (CS-A–mannitol coated) |
| Delivery Success Class | no |
| In Vivo Flag | yes |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | 8 µg DNA per mouse |
| Mixing Ratio | N/P = 10 |
| Formulation Format | Peptide–DNA nanocomplex with polymer coating |
| Formulation Components | M9 + plasmid DNA; CS-A–mannitol coating |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | C57BL/6 mouse lung |
| Administration Route | intratracheal |
| Output Type | biodistribution |
| Output Value | Widespread lung parenchyma distribution |
| Output Units | |
| Output Notes | Same M9 (CS-A–mannitol coated) formulation as in vitro studies; in vivo experiment assessed biodistribution only, not gene expression |
| Toxicity Notes | No acute toxicity reported |
| Curation Notes |