Sequence: WEARLARALARALARHLARALARALRACEA
| Experiment Id | EXP002104 |
|---|---|
| Paper | The osteogenic and angiogenic potential of microRNA-26a delivered via a non-viral delivery peptide f |
| Peptide | RALA |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | variable (N:P 1–15) |
| Rna Concentration | 1 µg/well |
| Mixing Ratio | N:P = 6 |
| Formulation Format | noncovalent peptide–DNA nanoparticle |
| Formulation Components | RALA + pmiR-26a |
| Size Nm | 74.00 |
| Zeta Mv | 21.00 |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | hBMSCs |
| Animal Model | |
| Administration Route | |
| Output Type | gene regulation / differentiation |
| Output Value | Upregulation of RUNX2, COL1, OCN, VEGF; increased mineralisation |
| Output Units | |
| Output Notes | Robust osteogenic and angiogenic differentiation in vitro |
| Toxicity Notes | No significant cytotoxicity |
| Curation Notes |