Sequence: RRRRRRR-ESRRB
| Experiment Id | EXP002125 |
|---|---|
| Paper | Supplementation With Cell-Penetrating Peptide-Conjugated Estrogen-Related Receptor β Improves the Fo |
| Peptide | CPP-ESRRB (7R-ESRRB) |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | 2 mg/mL |
| Rna Concentration | |
| Mixing Ratio | protein added to culture medium |
| Formulation Format | CPP–protein delivery |
| Formulation Components | 7R CPP + ESRRB recombinant protein |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | Mouse embryos (8-cell to blastocyst) |
| Animal Model | |
| Administration Route | |
| Output Type | gene upregulation / ICM formation |
| Output Value | Increased Oct4 and Nanog expression; increased ICM cell number |
| Output Units | |
| Output Notes | CPP-mediated protein delivery into embryos improved pluripotency markers |
| Toxicity Notes | No developmental toxicity; healthy pups born |
| Curation Notes |