Back to browse

EXP002234

Paper

Cell-penetrating peptides-modified nanocarrier for efficient, batch and noninvasive embryonic transfection (2025)

Peptide

TAT

Sequence: YGRKKRRQRRRC

RNA

mRNA / CRISPR

All experiment fields

Experiment Id EXP002234
Paper Cell-penetrating peptides-modified nanocarrier for efficient, batch and noninvasive embryonic transf
Peptide TAT
Delivery Success Class yes
In Vivo Flag yes
Uptake Confirmed yes
Label Confidence high
In Vitro Functional Effect
Endosomal Escape Evidence
Peptide Concentration 1–100 µg/mL nanoparticle
Rna Concentration 0.5–1 µg/mL
Mixing Ratio encapsulated in TNP
Formulation Format CPP-modified polymeric nanoparticle
Formulation Components TAT-TNP
Size Nm 120.00
Zeta Mv
Model Scope in_vivo
Model Type in vivo
Cell Lines Or Primary Cells
Animal Model zebrafish embryos; Penaeus monodon embryos
Administration Route immersion
Output Type reporter expression and gene editing
Output Value robust expression; 19–36% indels
Output Units
Output Notes Fig. 5–6
Toxicity Notes no developmental toxicity
Curation Notes