Sequence: CGGRRHHHHHRRR
| Experiment Id | EXP002248 |
|---|---|
| Paper | Arginine-rich hydrophobic polyethylenimine: Potent agent with simple components for nucleic acid del |
| Peptide | Hex-PEI-R5H5 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | no |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | pDNA: 200 ng; siRNA: 500 ng |
| Mixing Ratio | N/P 15 and 30 (reported improvements) |
| Formulation Format | PEI–peptide polyplex |
| Formulation Components | hexanoate-PEI + R5H5 |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | Neuro-2a; Neuro-2a/EGFPLuc |
| Animal Model | |
| Administration Route | |
| Output Type | reporter transfection efficiency (luciferase expression) |
| Output Value | |
| Output Units | |
| Output Notes | Improved gene transfection vs unmodified carrier at N/P 15 and 30. |
| Toxicity Notes | Lower cytotoxicity than PEI at comparable N/P (as reported). |
| Curation Notes |