Cell-penetrating Peptide for Enhanced Delivery of Nucleic Acids and Drugs to Ocular Tissues (2008)
Sequence: GGG(ARKKAAKA)4
| Experiment Id | EXP002302 |
|---|---|
| Paper | Cell-penetrating Peptide for Enhanced Delivery of Nucleic Acids and Drugs to Ocular Tissues |
| Peptide | POD |
| Delivery Success Class | no |
| In Vivo Flag | yes |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | |
| Peptide Concentration | nmol |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | CPP alone |
| Formulation Components | POD only |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | C57BL/6J mouse |
| Administration Route | subretinal / intravitreal / topical |
| Output Type | tissue penetration |
| Output Value | retinal and corneal uptake |
| Output Units | |
| Output Notes | Fluorescent localization in ocular tissues |
| Toxicity Notes | No acute toxicity reported |
| Curation Notes |