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EXP002316

Paper

Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide (2019)

Peptide

FAM-GYR

Sequence: 5-FAM-GYRPVHNIRGHWAPG

RNA

All experiment fields

Experiment Id EXP002316
Paper Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display p
Peptide FAM-GYR
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed no
Label Confidence high
In Vitro Functional Effect no
Endosomal Escape Evidence
Peptide Concentration µM range
Rna Concentration nM range
Mixing Ratio electrostatic assembly
Formulation Format peptide assembly / NLC
Formulation Components self-assembled peptide NLC
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells hCMEC/D3
Animal Model
Administration Route cell culture
Output Type uptake / gene silencing
Output Value TfR or Claudin-5 knockdown (only for CGY-based)
Output Units
Output Notes No cytotoxicity observed
Toxicity Notes 0
Curation Notes