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EXP002447

Paper

Chemical conjugation of an mRNA cap analogue with a cell-penetrating peptide as a potential membrane permeable translation inhibitor (2014)

Peptide

MPS

Sequence: AAVALLPAVLLALLAK

RNA

mRNA cap analogue

All experiment fields

Experiment Id EXP002447
Paper Chemical conjugation of an mRNA cap analogue with a cell-penetrating peptide as a potential membrane
Peptide MPS
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed no
Label Confidence high
In Vitro Functional Effect yes
Endosomal Escape Evidence
Peptide Concentration
Rna Concentration
Mixing Ratio
Formulation Format covalent conjugate
Formulation Components MPS–cap analogue conjugate
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells Biochemical / cell-free translation systems
Animal Model
Administration Route
Output Type translation inhibition
Output Value Cap analogue inhibits cap-dependent translation in vitro
Output Units
Output Notes Cell permeability discussed; biological testing limited to in vitro systems
Toxicity Notes
Curation Notes