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EXP002452

Paper

Role of nuclear localization signals in the DNA delivery function of Chikungunya virus capsid protein (2021)

Peptide

NLS2

Sequence: KKQPPKKKPAQKKKK

RNA

plasmid DNA

All experiment fields

Experiment Id EXP002452
Paper Role of nuclear localization signals in the DNA delivery function of Chikungunya virus capsid protei
Peptide NLS2
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed no
Label Confidence high
In Vitro Functional Effect no
Endosomal Escape Evidence
Peptide Concentration
Rna Concentration 1 μg plasmid DNA
Mixing Ratio peptide:DNA (w/w) up to 7:1
Formulation Format non-covalent complex
Formulation Components NLS2 peptide + plasmid DNA
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells HEK293T
Animal Model
Administration Route
Output Type reporter expression
Output Value No detectable GFP expression
Output Units
Output Notes DNA binding observed; intracellular trafficking not analyzed
Toxicity Notes ≥80% cell viability
Curation Notes