Sequence: RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP
| Experiment Id | EXP002513 |
|---|---|
| Paper | Suppression of tumor invasion and migration in breast cancer cells following delivery of siRNA again |
| Peptide | FITC-PR39 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | As above |
| Rna Concentration | 100 nM |
| Mixing Ratio | siRNA:PR39 = 1:90 |
| Formulation Format | CPP/siRNA noncovalent complex |
| Formulation Components | FITC-PR39 + Cy3-siRNA |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | 4T1 mouse breast cancer cells |
| Animal Model | |
| Administration Route | |
| Output Type | Fluorescence colocalization |
| Output Value | Cytoplasmic colocalization of peptide and siRNA |
| Output Units | |
| Output Notes | Used only for uptake/localization studies |
| Toxicity Notes | Not assessed separately |
| Curation Notes |