Sequence: AGYLLGKLLOOLAAAALOOLL
| Experiment Id | EXP002518 |
|---|---|
| Paper | PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid f |
| Peptide | PF14A |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | no |
| Peptide Concentration | Defined by molar ratio |
| Rna Concentration | 25–200 nM |
| Mixing Ratio | MR 3–20 (optimal MR5) |
| Formulation Format | Non-covalent CPP/SCO nanocomplex |
| Formulation Components | PF14A + SCO-Luc |
| Size Nm | 150.00 |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HeLa pLuc705; mdx mouse myotubes |
| Animal Model | |
| Administration Route | |
| Output Type | Splice correction |
| Output Value | High (PF14) / negligible (PF14A) |
| Output Units | |
| Output Notes | Luciferase restoration or dystrophin exon skipping |
| Toxicity Notes | Low toxicity |
| Curation Notes |