Peptide Nanocarriers for Targeted Delivery of Nucleic Acids for Cancer Therapy (2025)
Sequence: Fmoc-RR-Cycle(MEHRM)EW
| Experiment Id | EXP002566 |
|---|---|
| Paper | Peptide Nanocarriers for Targeted Delivery of Nucleic Acids for Cancer Therapy |
| Peptide | P |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | Peptide–ASO self-assembled nanocomplex |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | MCF7; HUVEC |
| Animal Model | |
| Administration Route | |
| Output Type | ASO gene knockdown and uptake |
| Output Value | Moderate Bcl-2 knockdown; non-selective uptake |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |