Sequence: RQIKIWFQNRRMKWKK
| Experiment Id | EXP002571 |
|---|---|
| Paper | Blood pressure reduction through brain delivery of nanoparticles loaded with plasmid DNA encoding an |
| Peptide | Penetratin |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | Peptide-functionalized liposome |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | Primary rat neurons, astrocytes, endothelial cells |
| Animal Model | |
| Administration Route | |
| Output Type | Gene knockdown |
| Output Value | AT1r mRNA significantly reduced |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |