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BPP8

Peptide ID

PEPTIDE000467

Raw sequence

TPA-mPEG-rllrkrlkrlhsalrvrl

Clean backbone

RLLRKRLKRLHSALRVRL

Tokenized backbone

R-L-L-R-K-R-L-K-R-L-H-S-A-L-R-V-R-L

Sequence engineering

Stereochemistry

D-form

Modifications

Retro-inverso D-peptide for RI variants; HA2 endosomal escape where indicated; PMO conjugated via thiol–maleimide

Sequence length

18

Noncanonical residues

Experiments

• EXP000533 from Efficient systemic CNS delivery of a therapeutic antisense oligonucleotide with…