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Ac-E(Chol)E(Chol)E(Chol)-HHH-YGRKKRRQRRR

Peptide ID

PEPTIDE000524

Raw sequence

Tat peptide core with variable His repeats and cholesterol–glutamate lipid (see Fig. 4A for exact composition)

Clean backbone

EEEHHHYGRKKRRQRRR

Tokenized backbone

E-E-E-H-H-H-Y-G-R-K-K-R-R-Q-R-R-R

Sequence engineering

Stereochemistry

Modifications

Cholesterol–glutamate lipidation; oligo-histidine pH-sensitive segment

Sequence length

17

Noncanonical residues

Experiments

• EXP000590 from Lipid-modified cell-penetrating peptide-based self-assembly micelles for co-del…