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CPP-B conjugate (M23D-B, dystrophin-targeting PPMO)

Peptide ID

PEPTIDE000990

Raw sequence

RXRRBRRXRRBRXB

Clean backbone

RAHXRRBLARRAHXRRBLARAHXBLA

Tokenized backbone

R-AHX-R-R-BLA-R-R-AHX-R-R-BLA-R-AHX-BLA

Sequence engineering

Stereochemistry

Modifications

X = 6-aminohexanoic acid (Ahx); B = β-alanine

Sequence length

26

Noncanonical residues

Experiments

• EXP001212 from Sustained Dystrophin Expression Induced by Peptide-conjugated Morpholino Oligom…