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KALA

Peptide ID

PEPTIDE001106

Raw sequence

WEKLAKALAKALAKHLAKALAKALKA-NH2

Clean backbone

WEKLAKALAKALAKHLAKALAKALKA

Tokenized backbone

W-E-K-L-A-K-A-L-A-K-A-L-A-K-H-L-A-K-A-L-A-K-A-L-K-A

Sequence engineering

C-terminal amidation

Stereochemistry

L-form

Modifications

Stearylated KALA (STR-KALA) on MITO-Porter surface (10 mol% of total lipids); cationic amphipathic CPP; plus Cholesterol-linked RNase P (RP) mitochondrial RNA aptamer (Chol-RP) added to surface (typically 4 mol% of total lipids) to enhance uptake/mitochondrial targeting

Sequence length

26

Noncanonical residues

Experiments

• EXP001418 from Mitochondrial transgene expression via an artificial mitochondrial DNA vector i…
• EXP001420 from Mitochondrial transgene expression via an artificial mitochondrial DNA vector i…