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PepFect14 (PF14)

Peptide ID
PEPTIDE001335
Raw sequence
Stearyl-AGYLLGKLLOOLAAAALOOLL-NH2 (O = ornithine)
Clean backbone
AGYLLGKLLORNORNLAAAALORNORNLL
Tokenized backbone
A-G-Y-L-L-G-K-L-L-ORN-ORN-L-A-A-A-A-L-ORN-ORN-L-L
Sequence engineering
Stearyl
Stereochemistry
Modifications
Stearylated amphipathic TP10-based CPP containing ornithines (PepFect14); forms polyplexes with anionic ASO; reported to induce endosomal release.
Sequence length
29
Noncanonical residues

Experiments