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CREKA (tumor-homing peptide) — C-NP

Peptide ID

PEPTIDE001485

Raw sequence

CREKA

Clean backbone

CREKA

Tokenized backbone

C-R-E-K-A

Sequence engineering

Stereochemistry

L-form

Modifications

CPP-modified redox-responsive polymer: GALA or CREKA conjugated to MAL-PEG-SS-PEI (PEG2k–SS–PEI25k). Disulfide bond enables GSH-triggered release. Peptide coupling: maleimide-terminated PEG-SS-PEI reacted with thiol-terminated peptide (1:1) then dialyzed/lyophilized.

Sequence length

5

Noncanonical residues

Experiments

• EXP001947 from Co-delivery of EGFR and BRD4 siRNA by cell-penetrating peptides-modified redox-…