Ab-CPP-LSP-siRNA (cetuximab–PEG–LMWP–AANL–siRNA; ARC)

Peptide ID: PEPTIDE001512
Raw sequence: VSRRRRGGRRRRRRAANL
Clean backbone: VSRRRRGGRRRRRRAANL
Tokenized backbone: V-S-R-R-R-R-G-G-R-R-R-R-R-R-A-A-N-L
Sequence engineering
Stereochemistry
Modifications: LMWP CPP fused to legumain substrate AANL; conjugated to siRNA via OPSS-PEG-NHS (~3.5 kDa) with disulfide linkage; further coupled to anti-EGFR antibody (cetuximab).
Sequence length: 18
Noncanonical residues

Experiments