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WRAP5

Peptide ID

PEPTIDE001895

Raw sequence

LLRLLRWWWRLLRLL

Clean backbone

LLRLLRWWWRLLRLL

Tokenized backbone

L-L-R-L-L-R-W-W-W-R-L-L-R-L-L

Sequence engineering

WRAP5 is a 15-aa tryptophan/arginine/leucine-rich amphipathic cell-penetrating peptide; reported in related WRAP literature as NH2-LLRLLRWWWRLLRLL-CONH2. In this paper, WRAP5 forms non-covalent peptide-based nanoparticles with siRNA at R = 20.

Stereochemistry

L-amino acids inferred; no D-amino acids reported in this paper.

Modifications

N-terminal amine and C-terminal amide inferred from related WRAP5 literature; non-covalent complexation with siRNA; no covalent peptide-RNA conjugation.

Sequence length

15

Noncanonical residues

Experiments

• EXP002478 from In Vivo Follow-Up of Gene Inhibition in Solid Tumors Using Peptide-Based Nanopa…
• EXP002479 from In Vivo Follow-Up of Gene Inhibition in Solid Tumors Using Peptide-Based Nanopa…
• EXP002480 from In Vivo Follow-Up of Gene Inhibition in Solid Tumors Using Peptide-Based Nanopa…