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Ala12

Peptide ID
PEPTIDE001912
Raw sequence
Stearoyl-AGYLLGKLLKKAAAAALKKLL-NH2
Clean backbone
AGYLLGKLLKKAAAAALKKLL
Tokenized backbone
A-G-Y-L-L-G-K-L-L-K-K-A-A-A-A-A-L-K-K-L-L
Sequence engineering
single-point PF14-Lys analogue Ala12; N-terminal stearoylation; C-terminal amidation; net charge +5; predicted α-helicity ~71; HLB 11.59.
Stereochemistry
L-amino-acid peptide; no D-amino acids reported; fatty-acylated CPP
Modifications
N-terminal stearic acid (C18) and C-terminal amide; noncovalent CPP/mRNA nanoparticle formation.
Sequence length
21
Noncanonical residues

Experiments