siRNA

Linked experiment: EXP000616

Linked peptide: PII

Linked paper: Design of cyclic RGD-conjugated Aib-containing amphipathic helical peptides for targeted delivery of small interfering RNA (2016)

RNA overview

RNA Type: siRNA
Payload/target: anti-luciferase (firefly luciferase) siRNA (21 nt)
Target gene/transcript: firefly luciferase; luciferase

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:CUUACGCUGAGUACUUCGAdTdT; antisense:UCGAAGUACUCAGCGUAAGdTdT
Sense strand: CUUACGCUGAGUACUUCGAdTdT
Antisense strand: UCGAAGUACUCAGCGUAAGdTdT

Chemical modifications

RNA modifications: dTdT 3' overhangs; AlexaFluor488-labeled sense strand used for uptake/CLSM assays