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ASO

Linked experiment: EXP000627

Linked peptide: L-R9

Linked paper: Delivery of antisense oligonucleotides for splice-correction of androgen receptor pre-mRNA in castration-resistant prostate cancer models using cell-penetrating peptides (2022)

RNA overview

RNA Type
ASO
Payload/target
AON-ISE targeting androgen receptor intronic splicing enhancer (AR-V7)
Target gene/transcript
androgen receptor intronic splicing enhancer

Sequence information

Sequence reported in source article
no
RNA sequence
not reported
Sense strand
Antisense strand

Chemical modifications

RNA modifications
Phosphorothioate backbone; 2′-O-methyl ribose; Cy3/AF568 labeled variants for uptake