siRNA

Linked experiment: EXP000633

Linked peptide: EB1

Linked paper: Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cells in vitro (2024)

RNA overview

RNA Type: siRNA
Payload/target: anti–BCR-ABL1 siRNA
Target gene/transcript: BCR-ABL1

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:CCGGUGUGCUUCGACAACUTT; antisense:AGUUGUCGAAGCACACCGGTT
Sense strand: CCGGUGUGCUUCGACAACUTT
Antisense strand: AGUUGUCGAAGCACACCGGTT

Chemical modifications

RNA modifications: dTdT overhangs; ROX/JOE labeled variants for uptake; 3' dTdT/TT overhang