ASO

Linked experiment: EXP000895

Linked peptide: mitFect9

Linked paper: Intracellular delivery of therapeutic antisense oligonucleotides targeting mRNA coding mitochondrial proteins by cell-penetrating peptides (2020)

RNA overview

RNA Type: ASO
Payload/target: UCP2 (cytosolic mRNA)
Target gene/transcript: cytosolic

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:GGGACUGUAGCUCAAUUGGUAGAGCAUCTTTGAAACCAACCATGATTC
Sense strand: GGGACUGUAGCUCAAUUGGUAGAGCAUCTTTGAAACCAACCATGATTC
Antisense strand

Chemical modifications

RNA modifications: D-arm modified 2'-OMe chimeric antisense (tRNA D stem-loop import signal)