ASO

Linked experiment: EXP000906

Linked peptide: mitFect9

Linked paper: Intracellular delivery of therapeutic antisense oligonucleotides targeting mRNA coding mitochondrial proteins by cell-penetrating peptides (2020)

RNA overview

RNA Type: ASO
Payload/target: COXII (mitochondrial mRNA)
Target gene/transcript: mitochondrial

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:GGGACUGUAGCUCAAUUGGUAGAGCAUCUUGCGCUGCAUGUGCCAU
Sense strand: GGGACUGUAGCUCAAUUGGUAGAGCAUCUUGCGCUGCAUGUGCCAU
Antisense strand

Chemical modifications

RNA modifications: D-arm modified antisense 2'-OMe RNA (tRNA D stem-loop import signal)