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aptamer

Linked experiment: EXP000913

Linked peptide: T7

Linked paper: Enhanced target cell specificity and uptake of lipid nanoparticles using RNA aptamers and peptides (2021)

RNA overview

RNA Type

aptamer

Payload/target

G-3 (CCR5) RNA aptamer + Cy5 DNA probe (Cy5/TCTATCAATCTATCA)

Target gene/transcript

not reported

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:GGGAGGACGAUGCGGAAUUGAGGGACCACGCGCUGCUUGUUGUGAUAAGCAGUUUGUCGUGAUGGCAGACGACUCGCCCGA

Sense strand

GGGAGGACGAUGCGGAAUUGAGGGACCACGCGCUGCUUGUUGUGAUAAGCAGUUUGUCGUGAUGGCAGACGACUCGCCCGA

Antisense strand

Chemical modifications

RNA modifications

2'-fluoro + 2'-O-methyl bases; 3-carbon linker (XXXXXX), sticky-bridge motif, 3' aminoC6; annealed to complementary Cy5-DNA probe