RNA, unspecified

Linked experiment: EXP000968

Linked peptide: P4

Linked paper: Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery (2024)

RNA overview

RNA Type: RNA, unspecified
Payload/target: ERα (estrogen receptor alpha) decoy / target protein: ERα
Target gene/transcript: not reported

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:GTCAGGTCACAGTGACCTGATCAAAGTTAA; antisense:uuaacuuugATCAGGTCACTGTGTGACCTGAC
Sense strand: GTCAGGTCACAGTGACCTGATCAAAGTTAA
Antisense strand: uuaacuuugATCAGGTCACTGTGTGACCTGAC

Chemical modifications

RNA modifications: LCL161 (IAP ligand) conjugated to 5′ end of forward strand (LCL-HDO-F); reverse strand contains 9-nt RNA segment (lowercase in SI) and P4 on 5′ end