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siRNA

Linked experiment: EXP001018

Linked peptide: All L-penetramax

Linked paper: To conjugate or not to conjugate? evaluating the potential use of cell-penetrating peptides for conjugation or complexation with oligonucleotides by surface plasmon resonance (2025)

RNA overview

RNA Type

siRNA

Payload/target

Model siRNA (used for SPR binding; not a therapeutic delivery study)

Target gene/transcript

Model

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:CCUGGUUCCUGGAACAAUUU; antisense:AAUUGUUCCAGGAAACAGGUU

Sense strand

CCUGGUUCCUGGAACAAUUU

Antisense strand

AAUUGUUCCAGGAAACAGGUU

Chemical modifications

RNA modifications

5′-biotinylated passenger/sense strand (NHS-PEG4-biotin); duplex siRNA (see Table 1 in paper for sequences/mass)