siRNA

Linked experiment: EXP001101

Linked peptide: CPP

Linked paper: Macrophage membrane- and cRGD-functionalized thermosensitive liposomes combined with CPP to realize precise siRNA delivery into tumor cells (2022)

RNA overview

RNA Type: siRNA
Payload/target: Negative-control siRNA in HepG2 xenograft tumors
Target gene/transcript: Negative-control

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:UGUAGAUGGACUUAAACUCdTdT; antisense:GAGUUUAAGUCCAUCUACAdTdT
Sense strand: UGUAGAUGGACUUAAACUCdTdT
Antisense strand: GAGUUUAAGUCCAUCUACAdTdT

Chemical modifications

RNA modifications: Negative-control siRNA duplex (sense 5′-UGUAGAUGGACUUAAACUCdTdT-3′; antisense 5′-GAGUUUAAGUCCAUCUACAdTdT-3′); CPP conjugated via disulfide to thiol-modified siRNA (C-si.NC).