siRNA

Linked experiment: EXP001168

Linked peptide: LAH4-L1

Linked paper: Reversal of ovarian cancer multidrug resistance by a combination of LAH4-L1-siMDR1 nanocomplexes with chemotherapeutics (2018)

RNA overview

RNA Type: siRNA
Payload/target: siMDR1 (targets MDR1/P-gp)
Target gene/transcript: not reported

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:CAGAAAGCUUAGUACCAAAdTdT; antisense:UUugGUACUAAGCUUUCugdTdC
Sense strand: CAGAAAGCUUAGUACCAAAdTdT
Antisense strand: UUugGUACUAAGCUUUCugdTdC

Chemical modifications

RNA modifications: dTdT overhangs (standard siRNA); 3' dTdT/TT overhang