ASO

Linked experiment: EXP001195

Linked peptide: B peptide

Linked paper: Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function (2008)

RNA overview

RNA Type: ASO
Payload/target: Dystrophin exon 23 splice donor (mdx mouse) – exon skipping to restore reading frame
Target gene/transcript: not reported

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:GGCCAAACCTCGGCTTACCTGAAAT
Sense strand: GGCCAAACCTCGGCTTACCTGAAAT
Antisense strand

Chemical modifications

RNA modifications: 25mer phosphorodiamidate morpholino oligomer (PMO; sequence M23D: GGCCAAACCTCGGCTTACCTGAAAT)