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ASO

Linked experiment: EXP001228

Linked peptide: TP10 (Transportan 10)

Linked paper: Application of Cell-Penetrating Peptides (CPP) to Enhance the Efficacy of Antisense Peptide Nucleic Acids (PNA) Molecules Delivery (2025)

RNA overview

RNA Type

ASO

Payload/target

Fluo-PCSK9-PPT-EX1-Ahx-NLS (PCSK9-targeting PNA; sequence: Fluo-A-G-A-G-G-A-G-G-A-A-G-Ahx-Pro-Lys-Lys-Lys-Arg-Lys-Val-amide; MW 4477.62)

Target gene/transcript

PNA

Sequence information

Sequence reported in source article

yes

RNA sequence

Fluo-A-G-A-G-G-A-GG-A-A-G-Ahx-Pro-Lys-Lys-Lys-Arg-Lys-Val-amide

Sense strand

Antisense strand

Chemical modifications

RNA modifications

5/6-carboxyfluorescein (NHS-fluorescein); Ahx linker; C-terminal NLS peptide (PKKKRKV-amide).