siRNA

Linked experiment: EXP001299

Linked peptide: Tat analog (CPP) + AT1002 analog (TJ modulator)

Linked paper: Therapeutic Effects on Atopic Dermatitis by Anti-RelA Short Interfering RNA Combined with Functional Peptides Tat and AT1002 (2011)

RNA overview

RNA Type: siRNA
Payload/target: Mouse RelA (NF-κB p65) siRNA (siRelA) for atopic dermatitis therapy
Target gene/transcript: non-silencing

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:GGUGCAGAAAGAAGACAUUdTdT; antisense:AAUGUCUUCUUUCUGCACCdTdT
Sense strand: GGUGCAGAAAGAAGACAUUdTdT
Antisense strand: AAUGUCUUCUUUCUGCACCdTdT

Chemical modifications

RNA modifications: dTdT overhangs (per sequences in Table 1)