siRNA

Linked experiment: EXP001306

Linked peptide: Octaarginine (R8)

Linked paper: Cell penetrating peptide-mediated systemic siRNA delivery to the liver (2011)

RNA overview

RNA Type: siRNA
Payload/target: SR-BI (scavenger receptor class B member 1) endogenous gene in liver/hepatocytes
Target gene/transcript: SR-BI

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:GUCGCAUGGCUCAGAGAGUTT; antisense:ACUCUCUGAGCCAUGCGACTT
Sense strand: GUCGCAUGGCUCAGAGAGUTT
Antisense strand: ACUCUCUGAGCCAUGCGACTT

Chemical modifications

RNA modifications: Unmodified siRNA (21-mer; TT overhangs); Cy3-labeled SR-BI siRNA used for biodistribution/uptake assays