siRNA

Linked experiment: EXP001327

Linked peptide: Penetratin-derived CPP

Linked paper: Cell-penetrating peptide-siRNA conjugate loaded YSA-modified nanobubbles for ultrasound triggered siRNA delivery (2015)

RNA overview

RNA Type: siRNA
Payload/target: Human c-Myc (anti-c-Myc siRNA)
Target gene/transcript: c-Myc; anti-c-Myc

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:AACGUUAGCUUCACCAACAUUTT; antisense:AAUGUUGGUGAAGCUAACGUUTT
Sense strand: AACGUUAGCUUCACCAACAUUTT
Antisense strand: AAUGUUGGUGAAGCUAACGUUTT

Chemical modifications

RNA modifications: Thiol-modified siRNA strand for disulfide conjugation to CPP; fluorophore labels (FAM/Cy3) used in uptake/biodistribution studies