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siRNA

Linked experiment: EXP001555

Linked peptide: gPADLG82

Linked paper: Influences of chain length and conformation of guanidinylated linear synthetic polypeptides on nuclear delivery of siRNA with potential application in transcriptional gene silencing (2025)

RNA overview

RNA Type

siRNA

Payload/target

siGL4 (luciferase reporter knockdown in HeLa-Luc); Cy3-siRNA (distribution); siEF52 (TGS of EF1A in 293T; gPALG100 only)

Target gene/transcript

luciferase; Cy3-

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:CCGUCGUAUUCGUGAGCAATT; antisense:UUGCUCACGAAUACGACGGTT

Sense strand

CCGUCGUAUUCGUGAGCAATT

Antisense strand

UUGCUCACGAAUACGACGGTT

Chemical modifications

RNA modifications

Cy3 label for imaging; otherwise unmodified siRNA sequences (siGL4, siNC, siEF52)