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siRNA

Linked experiment: EXP001585

Linked peptide: Octaarginine (R8) in DSPE-PEG2000-R8 (post-inserted)

Linked paper: In Vitro Investigations of the Efficacy of Cyclodextrin-siRNA Complexes Modified with Lipid-PEG-Octaarginine: Towards a Formulation Strategy for Non-viral Neuronal siRNA Delivery (2013)

RNA overview

RNA Type

siRNA

Payload/target

pGL3 luciferase siRNA (exogenous) and GAPDH siRNA (endogenous); FAM-siRNA used for uptake

Target gene/transcript

luciferase; GAPDH; FAM-

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:CUUACGCUGAGUACUUCGA

Sense strand

CUUACGCUGAGUACUUCGA

Antisense strand

Chemical modifications

RNA modifications

FAM label on sense strand for uptake studies; otherwise unmodified siRNAs