ASO

Linked experiment: EXP001615

Linked peptide: R9 (nona-arginine)

Linked paper: The nuclear concentration required for antisense oligonucleotide activity in myotonic dystrophy cells (2019)

RNA overview

RNA Type: ASO
Payload/target: CAG5 (triplet repeat-targeting ASO; sequence mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG)
Target gene/transcript: repeat

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG
Sense strand: mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG*mC*mA*mG
Antisense strand

Chemical modifications

RNA modifications: Fully 2'-O-methyl (m) + phosphorothioate (*) 15-mer; Cy5 label at 5' used for imaging/quantitation in some experiments