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siRNA

Linked experiment: EXP001645

Linked peptide: RVG-9R

Linked paper: Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer’s therapy (2017)

RNA overview

RNA Type

siRNA

Payload/target

BACE1 gene; fluorescently labeled siRNA used as tracer

Target gene/transcript

labeled

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:CUGUUAUCAUGGAGGGCUU

Sense strand

CUGUUAUCAUGGAGGGCUU

Antisense strand

Chemical modifications

RNA modifications

6-FAM label at 3' end of sense strand; Sense: 5'-CUGUUAUCAUGGAGGGCUU-3' (6-FAM on 3' sense)