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siRNA

Linked experiment: EXP001653

Linked peptide: Penetratin (ANTP)

Linked paper: Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides (2011)

RNA overview

RNA Type
siRNA
Payload/target
Luciferase (siLUC)
Target gene/transcript
luciferase

Sequence information

Sequence reported in source article
yes
RNA sequence
sense:GCUAUGAAGCGCUAUGGGC
Sense strand
GCUAUGAAGCGCUAUGGGC
Antisense strand

Chemical modifications

RNA modifications
Duplex siRNA with 3' dTdT overhangs (both strands); complexed with spermidine (N/P 8:1) for encapsulation in PLGA nanoparticles