Back to browse

miRNA

Linked experiment: EXP001655

Linked peptide: CC9

Linked paper: Cationic microRNA-delivering nanovectors with bifunctional peptides for efficient treatment of PANC-1 xenograft model (2013)

RNA overview

RNA Type

miRNA

Payload/target

miR-34a (tumor suppressor microRNA); negative control miRNA used in controls

Target gene/transcript

not reported

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:UUCUCCGAACGUGUCACGUdTdT; antisense:ACGUGACACGUUCGGAGAAdTdT

Sense strand

UUCUCCGAACGUGUCACGUdTdT

Antisense strand

ACGUGACACGUUCGGAGAAdTdT

Chemical modifications

RNA modifications

Synthetic miR-34a mimic; FAM-siRNA used for uptake assay as fluorescent tracer (0.5–2 µg per well); 3' dTdT/TT overhang