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ASO

Linked experiment: EXP001706

Linked peptide: PRFR

Linked paper: Impact of different cell penetrating peptides on the efficacy of antisense therapeutics for targeting intracellular pathogens (2016)

RNA overview

RNA Type

ASO

Payload/target

anti-rpoA PNA (targets 5′ region of L. monocytogenes rpoA mRNA; sequence cgatcattcaaa)

Target gene/transcript

rpoA PNA; rpoA

Sequence information

Sequence reported in source article

no

RNA sequence

not reported

Sense strand

Antisense strand

Chemical modifications

RNA modifications

12-mer PNA conjugated to CPP via linker '-O-' (as in Table 1); PNA is DNA analogue (pseudopeptide backbone)