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pDNA

Linked experiment: EXP001719

Linked peptide: Tat–LK15

Linked paper: Delivery of therapeutic shRNA and siRNA by Tat fusion peptide targeting bcr–abl fusion gene in Chronic Myeloid Leukemia cells (2010)

RNA overview

RNA Type

pDNA

Payload/target

BCR–ABL fusion (B3A2 isoform) shRNA expression plasmid

Target gene/transcript

not reported

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:GCAGAGTTCAAAAGCCCTT

Sense strand

GCAGAGTTCAAAAGCCCTT

Antisense strand

Chemical modifications

RNA modifications

Targeting sequence (shRNA): 5′-GCAGAGTTCAAAAGCCCTT-3′; loop 5′-CTCAAGAGA-3′; cloned into pSilencer 2.0 U6 hygro