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siRNA

Linked experiment: EXP001720

Linked peptide: Tat–LK15

Linked paper: Delivery of therapeutic shRNA and siRNA by Tat fusion peptide targeting bcr–abl fusion gene in Chronic Myeloid Leukemia cells (2010)

RNA overview

RNA Type

siRNA

Payload/target

BCR–ABL fusion (B3A2) siRNA

Target gene/transcript

not reported

Sequence information

Sequence reported in source article

yes

RNA sequence

sense:GCAGAGUUCAAAAGCCCUU

Sense strand

GCAGAGUUCAAAAGCCCUU

Antisense strand

Chemical modifications

RNA modifications

Sequence: 5′-GCAGAGUUCAAAAGCCCUU-3′ (matches shRNA target region); Cy5-labelled siRNA used for uptake assays