siRNA

Linked experiment: EXP001732

Linked peptide: iRGD TPN (PEGylated vs non-PEG) biodistribution (healthy mice)

Linked paper: iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer (2018)

RNA overview

RNA Type: siRNA
Payload/target: siLuc
Target gene/transcript: tagged; VivoTag-S750

Sequence information

Sequence reported in source article: yes
RNA sequence: sense:UUCUCCGAACGUGUCACGUUU
Sense strand: UUCUCCGAACGUGUCACGUUU
Antisense strand

Chemical modifications

RNA modifications: VivoTag-S750 labeled siRNA used for near-IR organ scans (not a therapeutic endpoint); dye/fluorescent label