siRNA

Linked experiment: EXP001792

Linked peptide: Orexin-a peptide

Linked paper: Rational Design of a Biomimetic Cell Penetrating Peptide Library (2013)

RNA overview

RNA Type: siRNA
Payload/target: Coagulation Factor VII (FVII) in vivo silencing (liver-expressed protein)
Target gene/transcript: not reported

Sequence information

Sequence reported in source article: no
RNA sequence: not reported
Sense strand
Antisense strand

Chemical modifications

RNA modifications: Factor VII siRNA with 2′-O-methyl sugar modifications (to reduce TLR7 activation and improve stability).