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aptamer

Linked experiment: EXP001804

Linked peptide: R8-modified MITO-Porter (no RNA aptamer)

Linked paper: A Dual-Ligand Liposomal System Composed of a Cell-Penetrating Peptide and a Mitochondrial RNA Aptamer Synergistically Facilitates Cellular Uptake and Mitochondrial Targeting (2016)

RNA overview

RNA Type

aptamer

Payload/target

Mitochondrial targeting (RP/MRP/D-arm aptamer as targeting ligand); no gene-silencing payload delivered

Target gene/transcript

ligand

Sequence information

Sequence reported in source article

yes

RNA sequence

UCUCCCUGAGCUUCAGG

Sense strand

UCUCCCUGAGCUUCAGG

Antisense strand

Chemical modifications

RNA modifications

not reported