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siRNA

Linked experiment: EXP001827

Linked peptide: Ab-CPP-siRNA (cetuximab–PEG–LMWP–siRNA; no substrate control)

Linked paper: Antibody-siRNA conjugates (ARCs) using multifunctional peptide as a tumor enzyme cleavable linker mediated effective intracellular delivery of siRNA (2021)

RNA overview

RNA Type

siRNA

Payload/target

Uptake/activation imaging (FITC-labeled antibody + TAMRA-labeled siRNA)

Target gene/transcript

body

Sequence information

Sequence reported in source article

no

RNA sequence

not reported

Sense strand

Antisense strand

Chemical modifications

RNA modifications

TAMRA-labeled anti-EGFP siRNA used in confocal uptake studies; thiol-modified siRNA for conjugation.